Our research focuses on genetic epilepsy and will help us understand the roles of genes such as ASH1L and SLC13A5 through clinical patient studies and mouse models, advancing treatment options for these disorders and deepening the understanding of epilepsy.
The Liu Lab is Interested in developing and evaluating novel therapies, notably targeting tumor vasculatures.
The Liu Lab studies the seasonal clock and its roles in human health. We use a new seasonal primate model, the mouse lemur, and an interdisciplinary approach of molecular biology, genetics, omics, machine learning, and computational modeling. We also apply the mouse lemur primate model to study pathophysiology that is poorly represented in mice, with a focus on neurodegeneration, immunology, and metabolism.
We are interested in how epithelial tissues sense and respond to injury.
Xin Liu Lab is interested in understanding the regulation of transcription and chromatin dynamics underlying many fundamental biological processes including differentiation, development, and oncogenesis.
The Liu Lab is interested in the functions and mechanism of codon usage biases, circadian clocks, and non-coding RNA
The major interest of my lab is to understand the transcriptional regulatory mechanisms involved in human diseases with a focus on cardiovascular diseases and cancer.
Dr. LoBue's BRAIN lab, short for Brain Aging, Injury, and Modulation Lab, has two lines of research in the area of aging and neurodegenerative diseases. The lab investigates the later-in-life effects of traumatic brain injury, which involves understanding the potential risk associated with developing dementia and the underlying biological pathways. The lab also studies the effects of noninvasive brain stimulation in Alzheimer’s disease and related disorders with the goal of informing the development of new treatments.
Our mission is to better unravel the causes and mechanisms underlying tremor disorders as well as understand the clinical features of these disorders.
The Louros Lab uses a hybrid approach combining molecular biophysics, structural biology, and bioinformatics to investigate protein stability, misfolding, and aggregation, with a particular interest in neurodegenerative diseases.
We use in vivo models of ischemic acute kidney injury in mice, and in vitro model systems to perform detailed studies of proinflammatory genes activated by renal ischemia/reperfusion.
For decades, the field of tuberculosis (TB) immunology has focused on T cell mediated protection, yet Mycobacterium tuberculosis (Mtb) still impacts one in four individuals worldwide today.
The Luo lab studies hypoxia stress in human cancers with a focus on epigenetic and metabolic alterations.
The research interests of the Lux Lab lie in the development of novel nanomedicine platforms to diagnose and treat disease in vivo noninvasively.
The Ly Laboratory studies how cell cycle defects and mitotic errors shape the complex mutational landscape of human cancer genomes.
Our research aims to obtain a comprehensive picture of how genomic stability and chromatin dynamics affect neuronal functions, including learning behaviors, and to apply this knowledge to combat neurological disorders.
Using novel multi-omics approaches and model systems to treat pancreatic cancer
We study the molecular events that drive this process in a term pregnancy and how perturbation of these processes contribute to premature birth.
Medical Artificial Intelligence and Automation
Dr. Maldjian's ANSIR Lab is devoted to the application of novel image analysis methods (e.g. diffeomorphic registration, machine learning, graph theory, ASL) to research studies, as well as to robust clinical translation of these techniques.
We study how disseminated cancer cells survive and give rise to overt metastatic lesions.
Malloy Lab has all the tools necessary for students at all levels to lean about metabolic imaging of physiology and disease and I am excited to participate.
Malter Lab focuses on exploring and characterizing intracellular signaling pathways in the immune and nervous systems and identifying how defects/abnormalities can lead to disease.
The Mangelsdorf/Kliewer Lab studies two signal transduction pathways that offer new therapeutic potential for treating diseases such as diabetes, obesity, cancer, and parasitism.
