The Sharma Lab is interested in investigating intermediary metabolism utilizing carbon-13 stable isotope tracers in conjunction with magnetic resonance spectroscopy (MRS), magnetic resonance imaging (MRI), and mass spectrometry (MS).
The overall goal of our laboratory is to discover the processes in endothelial cells that govern cardiovascular and metabolic health and disease.
Shay Lab is interested in the relationships between aging and cancer and have focused on the role of the telomeres and telomerase in these processes.
The ultimate aim of the Shiloh Lab is to contribute to the development of vaccines and treatments for Mycobacterium tuberculosis (Mtb).
Our laboratory’s focus is to understand the intrinsic roles of lysosomes and their regulatory functions in cellular and organismal homeostasis, with the ultimate goal of identifying novel therapeutic targets for a wide range of disease conditions.
Our primary goal in Sieber Lab is to understand the dynamic changes in metabolic programs that support developmental and disease progression.
We aim to globally understand how the physical and chemical properties of materials affect interactions with biological systems in the context of improving therapies.
Leveraging powerful new cell-based and cell-free systems, high-speed fluorescence imaging, and in vitro reconstitution using purified components to understand how cellular organelles such as peroxisomes are formed, how they acquire their unique identities and functions, and how defects in these processes cause human disease.
The Smith Lab strives to develop enabling tools for organic synthesis, allowing bioactive molecules of great complexity to be prepared in a concise and sustainable fashion.
The Solmonson lab is interested in how the placenta senses and achieves metabolic homeostasis between the adult and fetal compartments during pregnancy.
Dr. Song's laboratory focuses on understanding the mechanisms of cell death, including apoptosis, ferroptosis, pH-dependent cell death, and immunogenic cell death.
Our lab aim is to discover and translate findings into diagnostic and therapeutic solutions for patients with allergy.
The Sorrell Laboratory utilizes integrative approaches that include metabolomics, transcriptomics, organoid cultures, live microcopy, and animal models, to investigate fundamental pathways that control the uptake of nutrients and the biosynthesis of macromolecules in proliferative cells.
The goal of the Center is to support pre-clinical research that uncovers the mechanisms of pediatric musculoskeletal disorders and explores potential new therapies.
Our laboratory is interested in investigating the molecular mechanisms of selenoproteins in health and disease.
The Stopschinski lab investigates molecular and cellular mechanisms that drive neurodegeneration in Alzheimer’s Disease and other tauopathies with the goal to find new diagnostic and therapeutic approaches for these conditions.
The main goals of the Strand Lab are to create accurate cellular atlases of the human and mouse lower urinary tract, characterize the molecular and cellular alterations in human lower urinary tract disease, and design new mouse models.
We investigate epigenome regulation of nervous system development and homeostasis. We are particularly interested in understanding how disruption of these mechanisms lead to neurological disorders.
The vision of the lab is to further understand the pathogenesis of autoimmunity of the central nervous system through basic science and translational research.
In the Suleiman Lab, we focus on studying the podocyte biology, specifically the actin dynamics and cytoskeleton. Our research includes examining the balance of Rac and RhoA, two members of the Rho small GTPases, in both healthy and diseased kidneys.
Sumber Lab conducts translational research that seeks to uncover the mysteries of cancer and develop powerful methods for its detection and cure.
