Our lab specializes in clinical and research informatics, with a diverse portfolio of projects that leverage electronic health record (EHR) data and multimodal research data to enhance clinical care and advance research in the neurosciences.
The Ruan Lab focuses its research on developing statistical methods and computational algorithms for multi-omics data with applications in complex human diseases.
Our lab studies how cells organize metabolic pathways to meet changing metabolic demands. We explore how higher-order enzyme assemblies and organelle dynamics create compartmentalized metabolic environments. By uncovering the spatiotemporal regulation of metabolism, we aim to reveal fundamental principles of metabolic control relevant to health and disease.
We study how biomolecular condensates organize gene regulation.
Saelices Lab employs crystallography and cryo-EM to study amyloid deposition and design anti-amyloid tools.
The Saha Lab.
Sakano Lab investigates FMRP's influence on auditory brainstem development in Fragile X Syndrome. We examine gene expression and its potential link to autism, auditory processing, hyperacusis, and tinnitus.
Our mission is to advance biomedical knowledge in Multiple Sclerosis and support investigators in Neurology using best practices and comprehensive biostatistics expertise.
We seek to understand how RNA/protein assemblies control cellular states, and how related pathways are hijacked by diseases of aging.
The Sandstrom Lab works to identify the fundamental molecular mechanisms through which the immune system can recognize pathogens and stress.
The Sankary Neuroethics Lab at UT Southwestern explores the ethical dimensions of neuroscience and neurosurgical innovation.
Satterthwaite Lab studies the signals that control B lymphocyte development, activation, and differentiation into antibody-secreting plasma cells, both normally and in autoimmune diseases such as lupus. We hope that by defining these events, we can reveal new approaches to modulate antibody responses therapeutically.
The Saunders Lab aims to advance our understanding of the bacterial domain of life using high throughput genetics to map the molecular interactions that underly cellular physiology.
The Saxena lab's research interests include Icodextin in high peritoneal transporters; Kremezin study in patients with chronic kidney disease; SV40 in focal segmental glomerulosclerosis; molecular studies in lupus nephritis.
The Schaffert Lab advances understanding of cognitive decline and recovery mechanisms by investigating (1) idiopathic normal pressure hydrocephalus, focusing on cognitive, neurobiological, and pathophysiological processes that shape impairment and postoperative recovery, and (2) long-term cognitive impairment and dementia following traumatic brain injury, with emphasis on identifying factors associated with persistent deficits, accelerated cognitive aging, and later-life neurodegenerative diagnoses.
The main focus in our laboratory is the identification and physiological characterization of adipocyte-specific gene products and the elucidation of pathways that are an integral part of the complex set of reactions that drive adipogenesis.
The Schoggins Lab studies innate immunity at the virus-host interface. We are interested in mechanisms of cellular antiviral defense and the role these responses play during viral disease.
What are the causes and consequences of cytoskeletal diversification?
The Seemann Lab studies the molecular mechanisms governing the function and inheritance of the mammalian Golgi apparatus.
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The Sguigna lab investigates the visual system in multiple sclerosis, and other neurological conditions, with the intent of leveraging technologies to further science both diagnostically and therapeutically.
We aim to characterize the ways in which reward systems vary from individual to individual and understand how this variation determines propensity for depression and addiction-like behavior.
The Shahmoradian lab investigates the roles of domain-specific neuronal proteins using advanced cryo-imaging techniques to understand their impact on cellular dynamics and neurological health.
Our lab researches Cerebellar Dysfunction, Brainstem Dysfunction, High-Throughput Screen, and Human Studies.
The Sharma Lab advances cardiovascular and transplant medicine through three integrated research areas:
