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Sun (Xiankai) Lab

The Sun Lab is focused on developing novel imaging probes for noninvasive assessment of specific biomarkers implicated in disease initiation, progression, or regression, and exploring the translational roles of imaging probes and/or methodologies in clinical medicine practice with the ultimate goal to improve the outcome of patient care.

  • Xiankai Sun, Ph.D.
Biomedical Engineering

Syeda Lab

Our lab's focus is to develop novel tools aimed at understanding ion channel physiology and molecular mechanism in an isolated membrane environment.

  • Ruhma Syeda, Ph.D.
Piezo1 Ion channels Mechanotransduction Mechanically activated ion channels Lipid bilayers Single channels Electrophysiology
Molecular Biophysics Neuroscience

Tagliabracci Lab

The Tagliabracci Lab studies the phosphorylation of extracellular proteins by a novel family of secreted kinases. This kinase family is so different from canonical kinases that it was not included as a branch on the human kinome tree.

  • Vincent "Vinnie" Tagliabracci, Ph.D.
Pseudokinases
Cell and Molecular Biology Genetics, Development and Disease

Takahashi Lab

The Takahashi Lab is interested in understanding the genetic and molecular basis of circadian rhythms as well as other complex behaviors.

  • Joseph Takahashi, Ph.D.
Neuroscience

Tambar Lab

The Tambar Group develops new strategies and concepts in synthetic chemistry to address challenging problems in chemistry and biology.

  • Uttam K. Tambar, Ph.D.
Organic Chemistry
Organic Chemistry Biological Chemistry

Tamminga Lab

The lab investigates the nature and treatment of cognitive deficits commonly seen in schizophrenia and related disorders.

  • Carol A. Tamminga, M.D.
Psychosis
Clinical Psychology Neuroscience

Tang Lab

Under the guidance of director Dr. Daolin Tang, the research group focuses on basic, translational and clinical application research on damage-associated molecular patterns (DAMPs) signaling pathways. Inflammation is a fundamental response to infection and injury in all multicellular organisms. The danger hypothesis states that endogenous molecules (protein and non-protein) released during cell death or tissue damage can trigger inflammation in the absence of infection, collectively referred to as DAMPs. We are particularly interested in elucidating the molecular mechanisms underlying stress-induced cellular defense and cell death signaling in normal and cancer cells, and how release of DAMPs modulates immune responses in disease.

  • Daolin Tang, M.D., Ph.D.
molecular diagnostics Bacterial pathogenesis Tumor microenvironment pancreatic cancer Cell Death
Cancer Biology

Tatara Lab

The Tatara Laboratory applies engineering technologies to study and treat infectious diseases. We are particularly engaged in device-related infection, orthopedic immunology, and pathogen virulence on biomaterial surfaces. 

  • Alexander Tatara

Terada Lab

The Terada Lab is focused on several areas of cellular signaling which control basic mechanical and cell fate decision programs. 

  • Lance Terada, M.D.
Lung cancer
Cell and Molecular Biology

Terman Lab

Research in my laboratory focuses on better understanding the molecules and mechanisms that assemble axonal connections with a goal of utilizing this knowledge to encourage axons to reestablish their connections after trauma or disease.

  • Jonathan Terman, Ph.D.
Neuroscience

The Connected Aging Lab

The Connected Aging Lab is committed to advancing brain health and emotional well-being in older adults by developing inclusive, relationship-centered interventions that bridge science, clinical care, and community.

  • Kexin Yu, Ph.D.

Thinwa Lab

The Thinwa lab studies neurotropic viruses, host defense pathways, autophagy and brain development.

  • Josephine Thinwa, M.D., Ph.D.
infectious disease Immunology
Molecular Microbiology

Thomas Lab

In our lab, we focus on the mechanisms of cerebrovascular reactivity, exploring how blood vessels in the brain respond to changes in carbon dioxide, blood pressure, and other stimuli. 

  • Binu Thomas
alzheimer's disease aging
Biomedical Engineering

Tong Lab

The Tong lab studies the cellular and molecular mechanisms of cardiovascular diseases associated with systemic metabolic disorders, particularly heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF), with an eye toward translating these findings into innovative solutions to clinical problems.

  • Dan Tong, M.D., Ph.D.
Heart Failure with Preserved Ejection Fraction Atrial Fibrillation Clonal Hematopoiesis
Cell and Molecular Biology Genetics, Development and Disease

Toprak Lab

We investigate genetic and molecular basis of phenotypic diversity observed in nature by using a range of methodologies such as whole genome sequencing, fluidics, long-term evolution experiments, and large-scale combinatorial mutagenesis. 

  • Erdal Toprak, Ph.D.
Biomedical Engineering Molecular Biophysics

Toto Lab

My research interests include prevention of progression of renal diseases, diagnoses, and management of lipid disorders in renal disease, hypertensive nephrosclerosis, the role of angiotensin II converting enzyme inhibitors, and angiotensin II receptor blockers in renal disease. 

  • Robert Toto, M.D.
Translational Research diabetic nephrology

Tower Lab

The Tower lab integrates multi-omics-based approaches in the fields of musculoskeletal development, homeostasis, repair and regeneration. 

  • Robert Tower, Ph.D.
Genetics, Development and Disease

Trivedi Lab (CDRC)

The Center for Depression Research and Clinical Care (CDRC) is nationally recognized for its cutting-edge research in unipolar and bipolar depression. The research conducted within the center brings better understanding of the causes of depression, identifies effective new treatments, and improves existing ones.

  • Madhukar H. Trivedi, M.D.
mood disorders research Translational Research microbiome
Clinical Psychology

TRUST Lab

Translational Research in UltraSound Theranostics (TRUST) Lab at UT Southwestern

  • Robert Mattrey, M.D.
Biomedical Engineering

Tsai Lab

Tsai Lab studies the cellular and molecular mechanisms of synapse and neural circuit development.

  • Peter Tsai M.D. Ph.D
Autism neurodevelopmental disorders cerebellum
Neuroscience

Tu Lab

The Tu Lab is investigating how a variety of cellular processes and decisions are coordinated with metabolic state, and how the dysregulation of these mechanisms might be linked to disease and aging.

  • Benjamin P. Tu, Ph.D.
metabolism Epigenetics RNA gene expression yeast Neurodegeneration Cancer
Biological Chemistry

Turer Lab

The Turer Lab is interested in finding genes with novel functions in intestinal immune homeostasis. Our projects generally involve a mix of experimental approaches examining both the intestinal epithelium as well as hematopoietic causes of intestinal inflammation.

  • Emre Erol Turer, M.D., Ph.D.
Cell and Molecular Biology Immunology

Tzen Lab

spinal cord injury, wound, pressure ulcer

  • Yi-Ting Tzen, Ph.D.

Ufret-Vincenty Lab

The goal of the Ufret-Vincenty Lab is to develop therapeutic strategies for age-related macular degeneration (AMD).

  • Rafael L. Ufret-Vincenty, M.D.
AMD macular degeneration choroidal neovascularization cnv

van Oers Lab

Children with in-born errors of immunity are prone to life-threatening viral, bacterial, and fungal infections. We study the causes of their immune system problems, combining clinical insights and mouse models genocopying the various mutations. This work includes a profiling of immune responses to infections (e.g., COVID-19) in normal healthy individuals along with different patient populations (e.g. 22q11.2 deletion syndrome).

  • Nicolai S.C. van Oers, Ph.D.
Thymus functions Immunology Human Disease Mapping
Immunology Molecular Microbiology