The goal of the Center is to support pre-clinical research that uncovers the mechanisms of pediatric musculoskeletal disorders and explores potential new therapies.
Our laboratory is interested in investigating the molecular mechanisms of selenoproteins in health and disease.
The Stopschinski lab investigates molecular and cellular mechanisms that drive neurodegeneration in Alzheimer’s Disease and other tauopathies with the goal to find new diagnostic and therapeutic approaches for these conditions.
The Stowe Lab conducts both bench and clinical research with the goal of deepening the understanding of the etiology of stroke as well as finding better therapies for those who have suffered a stroke.
The main goals of the Strand Lab are to create accurate cellular atlases of the human and mouse lower urinary tract, characterize the molecular and cellular alterations in human lower urinary tract disease, and design new mouse models.
We investigate epigenome regulation of nervous system development and homeostasis. We are particularly interested in understanding how disruption of these mechanisms lead to neurological disorders.
The vision of the lab is to further understand the pathogenesis of autoimmunity of the central nervous system through basic science and translational research.
Sumber Lab conducts translational research that seeks to uncover the mysteries of cancer and develop powerful methods for its detection and cure.
The Sun Lab studies the most numerous cells in the brain, called “glial cells”.
Our research focuses on developing and testing novel immunotherapies for meningiomas (the most common brain tumors in adults) as well as on understanding the tumor immune microenvironment of meningiomas and other skull base tumors.
The Sun Lab is focused on developing novel imaging probes for noninvasive assessment of specific biomarkers implicated in disease initiation, progression, or regression, and exploring the translational roles of imaging probes and/or methodologies in clinical medicine practice with the ultimate goal to improve the outcome of patient care.
Our lab's focus is to develop novel tools aimed at understanding ion channel physiology and molecular mechanism in an isolated membrane environment.
The Tagliabracci Lab studies the phosphorylation of extracellular proteins by a novel family of secreted kinases. This kinase family is so different from canonical kinases that it was not included as a branch on the human kinome tree.
The Takahashi Lab is interested in understanding the genetic and molecular basis of circadian rhythms as well as other complex behaviors.
The Tambar Group develops new strategies and concepts in synthetic chemistry to address challenging problems in chemistry and biology.
Under the guidance of director Dr. Daolin Tang, the research group focuses on basic, translational and clinical application research on damage-associated molecular patterns (DAMPs) signaling pathways. Inflammation is a fundamental response to infection and injury in all multicellular organisms. The danger hypothesis states that endogenous molecules (protein and non-protein) released during cell death or tissue damage can trigger inflammation in the absence of infection, collectively referred to as DAMPs. We are particularly interested in elucidating the molecular mechanisms underlying stress-induced cellular defense and cell death signaling in normal and cancer cells, and how release of DAMPs modulates immune responses in disease.
The Terada Lab is focused on several areas of cellular signaling which control basic mechanical and cell fate decision programs.
Research in my laboratory focuses on better understanding the molecules and mechanisms that assemble axonal connections with a goal of utilizing this knowledge to encourage axons to reestablish their connections after trauma or disease.
Texas Computational Memory Lab research focuses on analyzing the neural activity that gives rise to successful memories and facilitates memory retrieval.
Research in the Thermal and Vascular Physiology Laboratory focuses on neural control of the cardiovascular system and how different stressors influence that control in healthy, diseased, and injured individuals, such as:
The Thinwa lab studies neurotropic viruses, host defense pathways, autophagy and brain development.
This information will appear on the lab listing page.The Tong lab studies the cellular and molecular mechanisms of cardiovascular diseases associated with systemic metabolic disorders, particularly heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF), with an eye toward translating these findings into innovative solutions to clinical problems.
