We investigate genetic and molecular basis of phenotypic diversity observed in nature by using a range of methodologies such as whole genome sequencing, fluidics, long-term evolution experiments, and large-scale combinatorial mutagenesis.
My research interests include prevention of progression of renal diseases, diagnoses, and management of lipid disorders in renal disease, hypertensive nephrosclerosis, the role of angiotensin II converting enzyme inhibitors, and angiotensin II receptor blockers in renal disease.
The Tower lab integrates multi-omics-based approaches in the fields of musculoskeletal development, homeostasis, repair and regeneration.
The Center for Depression Research and Clinical Care (CDRC) is nationally recognized for its cutting-edge research in unipolar and bipolar depression. The research conducted within the center brings better understanding of the causes of depression, identifies effective new treatments, and improves existing ones.
Translational Research in UltraSound Theranostics (TRUST) Lab at UT Southwestern
Tsai Lab studies the cellular and molecular mechanisms of synapse and neural circuit development.
The Tu Lab is investigating how a variety of cellular processes and decisions are coordinated with metabolic state, and how the dysregulation of these mechanisms might be linked to disease and aging.
The Turer Lab is interested in finding genes with novel functions in intestinal immune homeostasis. Our projects generally involve a mix of experimental approaches examining both the intestinal epithelium as well as hematopoietic causes of intestinal inflammation.
spinal cord injury, wound, pressure ulcer
The goal of the Ufret-Vincenty Lab is to develop new therapeutic strategies for age-related macular degeneration (AMD).
Children with in-born errors of immunity are prone to life-threatening viral, bacterial, and fungal infections. We study the causes of their immune system problems, combining clinical insights and mouse models genocopying the various mutations. This work includes a profiling of immune responses to infections (e.g., COVID-19) in normal healthy individuals along with different patient populations (e.g. 22q11.2 deletion syndrome).
The Varadarajan Lab is interested in rebuilding neural circuits and restoring sensory function impaired by injury or disease.
Our team at UT Southwestern is conducting the study Improving Chronic Disease Management with Pieces (IDC-Pieces) in patients with coexistent chronic kidney disease, diabetes and hypertension.
Dr. Vega and co-workers have discovered three other causes of high LDL. First, she found that some patients have abnormal LDL particles that cannot be removed from circulation because the abnormal LDL does not recognize the receptors.
The Vernino Lab focuses on the mechanisms of autoimmune disorders of the nervous system, especially those associated with neurological autoantibodies. We use a variety of techniques including histology, and immunology. This research is complemented by clinical therapeutic trials studying novel treatments for autoimmune encephalitis and autonomic disorders.
The main focus of the Vinogradov Lab is developing MRI methods that are based on the intrinsic biochemical processes and physical properties of the tissue: chemical exchange rearrangements, molecular networks, and relaxation.
Our research efforts are currently focused in four areas of cancer research.
The Volk Lab's research focuses on the hippocampus as they research how the brain balances dynamic learning and persistent memory.
Dr. Vongpatanasin studies neural control of blood pressure and the influence of various hormones and antihypertensive agents on autonomic control of blood pressure in humans.
The research of Wai Lab focuses on female pelvic floor disorders and understanding the functional anatomy of the lower urinary tract and anal sphincter.
The Wakeland Lab utilizes state-of-the-art genomic strategies to investigate the diversity of the human and mouse immune systems.
The Wang Lab uses chemical biology tools to study the molecular mechanisms underlying interesting bacterial behaviors.
The broad research interest of Fei Wang lab is in dissecting molecular mechanisms of essential membrane-associated cellular events in eukaryotic cell development.
We apply advanced MRI technologies to study many different diseases.
Dr. Wang's research interests primarily involve the development of statistical methodologies for the design and analysis of clinical trials, as well as the evaluation of correlated data and repeated measurements. Her specific focus has been on power analysis, experimental design, and sample size determination for longitudinal studies using Frequentist and Bayesian approaches. Dr. Wang has also developed the methodologies that are very flexible and can accommodate various pragmatic issues such as longitudinal and clustered outcomes, random variability in cluster size, unbalanced randomization, complicated correlation structures, missing data, and small sample sizes. Those methodologies have achieved great performances across a broad spectrum of design configurations and made innovative contributions to clinical studies.
