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White, Perrin Lab - Labs - Research

The Whitehurst Lab uses RNAi-based functional genomics to identify gene products that support viability and/or modulate chemotherapeutic sensitivity in tumor cells. 

We are interested in understanding at a cellular level the neural control of energy balance and glucose metabolism, and elucidating how these events may participate in human disease.

Wilson Lab

Scientists in the Center for Pediatric Bone Biology and Translational Research work to discover the underlying causes of poorly understood musculoskeletal disorders in children, and to understand the fundamental steps that lead to disease.

We use live-cell microscopy, nano-rheology, and synthetic biology to understand oocyte ageing, embryogenesis, and cancer onset.

In our laboratory, we utilize molecular and cellular approaches to decipher mechanisms of extracellular matrix remodeling of the female reproductive tract in both physiologic states (e.g., during pregnancy, parturition, and the puerperium) and pathologic conditions (pelvic organ prolapse, urinary incontinence, and injury of the external anal sphincter).

The Wu Laboratory mainly focuses on using human primary nasal and oral epithelium culture to gain novel insights in virus-host interactions.

We are interested in the function of chromatin regulation of signaling pathways important for neural development, brain tumor growth and autism pathogenesis. 

The Wu Laboratory mainly focuses on using stem cell models to gain novel insights in mammalian development and develop regenerative medical applications.

The long-term goal of our lab is to understand the functions of ecDNA and how ecDNA is maintained in cancer. 

The Wu Lab focuses on understanding the molecular pathways that govern T cell differentiation and function during infection and cancer.

I am interested in developing computational models and algorithms for big data to predict patients' outcomes, which can help clinicians to tailor treatment plans for individual patients.

The focus of our current research is the biochemistry and molecular characterization of ABCG5/ABCG8 transporter, aiming at understanding the mechanism by which this transport system operates to translocate cholesterol cross membranes.

Our team is interested in developing computational models to predict patient outcomes, which will allow clinicians to tailor treatment plans for individual patients.

Welcome to the Xing Lab in the Eugene McDermott Center for Human Growth and Development!

Dr. Xu’s primary research interests include tissue engineering of the vocal fold, anatomy and physiology of voice production, and laryngeal biomechanics. 

The lab focuses on developing bioinformatics algorithms and deep learning models to identify new disease genes and therapeutic targets for human diseases, as well as development and maintenance of data management system for genomic and clinical databases.

Wei Xu Lab strives to achieve a mechanistic understanding of fundamental cognitive processes whose dysfunctions are implicated in neuropsychiatric disorders.

Our lab focuses on the neural dynamics for successful memory access and retrieval during episodic working memory tasks to elucidate the neural circuit mechanism in the hippocampal-cortical network.

Since I began studying the biological rhythms of insects during graduate school, I have been fascinated with the accuracy of the circadian timing system and the phenomenal influence of the circadian clock on almost all biological activities. This fascination has fueled my interest in learning about circadian rhythms for more than a quarter of a century.

The Yan Lab studies molecular mechanisms of innate immunity in infection, autoimmune diseases, cancer immunology and neurodegenative diseases.

The Yang Lab aims to overcome clinical unmet needs and help patients by developing and validating advanced radionuclide imaging technologies for positron emission tomography (PET) and single photon emission computed tomography (SPECT) imaging. Deep learning is an important engine for overcoming the current limitations (low spatial resolution, slow data acquisition, etc.) of PET and SPECT imaging. . 

Yao Laboratory identifies molecular and cellular mechanisms that determine the efficacy of vaccines and immunotherapies against infectious diseases and cancers.