Munshi Lab
The Munshi Lab is a dedicated group of scientists seeking to identify the molecular drivers of normal cardiac rhythm and disease-associated dysrhythmias.
- Nikhil Munshi, M.D., Ph.D.
The Munshi Lab is a dedicated group of scientists seeking to identify the molecular drivers of normal cardiac rhythm and disease-associated dysrhythmias.
Muto lab leverages both cutting-edge wet-lab and multi-omics approaches to understand gene regulatory mechanism driving kidney diseases. Current projects are focused on acute kidney injury and polycystic kidney disease.
The Nair-Gill Lab dissects the cellular infrastructure that dictates immune cell survival and fate decisions.
The mission of the Najafov Lab is to understand the role of cell death in physiology and disease. Our research is focused on necroptosis and how it can be targeted to develop novel strategies for treating cancer.
Shawna D. (Smith) Nesbitt, M.D., M.S., studies hypertension in African-Americans, insulin resistance, and hyperlipidemia.
We study bacterial colonization of the intestinal tract, to understand how both benign and pathological bacteria affect their environment. Our long-term goal is to treat intestinal diseases by genetically engineering bacteria in vivo.
The Ank Nijhawan research team is focused on improving outcomes for people living with or at risk for HIV, and ensuring their access to comprehensive healthcare and social support services. We also focus on individuals involved in the criminal legal system, and specifically the overlap of infectious diseases such as HIV, hepatitis, sexually transmitted infections and substance use.
The ultimate goal of the Nijhawan-De Branander Lab is to discover first in class drugs for the treatment of cancer.
We are dedicated to uncovering how G protein–coupled receptors (GPCRs) regulate metabolism and contribute to health and disease. Our research aims to translate these discoveries into new insights and therapeutic strategies.
Our research is focused on mechanisms underlying acute kidney injury and sepsis. Our laboratory has implicated mitochondrial maintenance via PGC1alpha and NAD+ as a novel pathway for resilience against acute physiological stressors.
Our laboratory has a particular interest in hepatic metabolism and its regulation by the immune system. We utilize genetic, epigenetic and proteomic approaches, combined with detailed physiological studies, to understand the complex mechanisms that causally link inflammation to metabolic dysfunction in obesity and fatty liver disease.
Translational biophotonics for noninvasive detection of systemic disease.
The goal of our research is to identify key immune checkpoints of gastrointestinal disorders that could be targeted for therapeutic intervention and drug development.
Leveraging cutting-edge genetic and chemical screens to uncover novel and enhanced therapeutics for cancer treatment.
The global focus of the Pulmonary Physiology Laboratory is the study of pulmonary exercise physiology, particularly as it pertains to pulmonary disease, normal aging, obesity, ventilatory control during exercise, applied respiratory physiology, and clinical cardiopulmonary exercise testing. The Lab consists of three separate investigative laboratories: the pulmonary function laboratory, the cardiopulmonary exercise physiology laboratory, and the body composition laboratory including DEXA imaging for the determination of percent body fat, lean body mass, bone content, visceral fat, overall fat distribution, and their effects on breathing.
We are broadly interested in how energy is regulated on a systems level during infection. Our current projects are focused on understanding the role that adipose tissue plays in the response to influenza and SARS-CoV2.
The Reddy Lab focuses on restoring effective antigen presentation to enhance anti-tumor immunity in breast cancers.
The Reinecker laboratory unravels and targets molecular mechanisms of key human genetic variants that cause chronic inflammatory diseases and cancer by creating novel genetic mouse and human organotypic model systems.
We are interested in the molecular mechanisms by which nuclear hormone receptors regulate lipid and carbohydrate metabolism in the liver, intestine, pancreatic islet, and central nervous system.
The Rohatgi Lab focuses on the role of reverse cholesterol transport in atheroprotection.
Research in the Rothermel Laboratory focuses on deciphering the molecular mechanisms that control cardiac structure and function during normal development and in response to pathological stress.
Satterthwaite Lab studies the signals that control B lymphocyte development, activation, and differentiation into antibody-secreting plasma cells, both normally and in autoimmune diseases such as lupus. We hope that by defining these events, we can reveal new approaches to modulate antibody responses therapeutically.
The Saxena lab's research interests include Icodextin in high peritoneal transporters; Kremezin study in patients with chronic kidney disease; SV40 in focal segmental glomerulosclerosis; molecular studies in lupus nephritis.